In honor of National Autism Month, I want to discuss chronic inflammatory response syndrome as it relates to the treatment of patients with autism.

Inflammation may be at the root of every chronic disease we see, especially neurological and behavioral chronic diseases. Either the problem is chronic inflammation of the body or disregulation in how the body controls chronic inflammation.

In both cases, the body convinces the hypothalamus area of the brain to treat the body as if it’s fighting off a virus infection for the remainder of its life.


Treating Autism with the Shoemaker Protocol


A pediatrician learned about the Shoemaker Protocol, developed by Dr. Ritchie Shoemaker to treat mold and other biotoxin exposures. It works by removing inflammation from the body, then rebooting that inflammation control system inside the brain so it no longer thinks it’s fighting off a virus. The pediatrician applied this protocol to a patient with PANS in autism and he was able to completely relieve the patient’s symptoms.

When I first met this one young lady, she was interacting with other people on a very limited basis. The only thing she ever said to me was, “Don’t look in my ears,” and she said that about every 30 seconds.

She had a biotoxin sensitivity that caused inflammation. After working to remove inflammation and starting her on medicine to remove the biotoxins accumulating in her body, the mother told me her daughter helped plan her own birthday party and actually played with her friends. In addition, this young lady stopped scripting, or repeating a phrase that’s just been said to her. The next time she came to my office, she was also able to tolerate my swabbing her nose and the back of her throat, something she wouldn’t have before.


Can the Shoemaker Protocol Help Others with Autism?


Autism is a very, very broad spectrum of conditions. While we’re nearly certain  inflammation is involved in all of them, we can’t say for sure the Shoemaker Protocol will cure all of them. It’s very likely a large percentage of those with autism will respond to the Shoemaker Protocol.

The Shoemaker Protocol is a very arduous process requiring dietary changes, changes in living conditions and mold remediation. It requires the use of some agents, most notably a vasoactive intestinal peptide, at the end of the sequence.

It may not be covered by insurance. Make sure you talk to a physician who has studied the Shoemaker Protocol thoroughly so they can guide you through the financial consequences and commitment of undertaking this treatment. Make sure home remediation is performed first and done in ways that don’t bankrupt or financially burden the family, or expose the household to more toxins in the process.

If I can help someone with autism in your family, please contact me at Pure Health Functional Family Medicine, call 317-559-2515 or email me at

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